Application of fingerprintmethodin functional food quality control

Project leader's name
Dr. Tran Thi Hong Hanh
Research hosting institution
Institute of Marine Biochemistry
Project duration
2016 - 2018
́Project’s budget
10,000 million VND
Classify
Excellent
Goal and objectives of the project

- Successful creation of a functional food assisted for prevention and treament of cancer.
- Successful application of fingerprint method in quality control of the created functional food.

Main results

- Theoretical results:
+ Isolation and structural identification of 116 compounds from 10 medicinal plants collected in Vietnam.
+ Successfulestablishmentof a process for assessingquality of the created functional food product.
+ Successfulestablishment of a process for measuringconcentration of heavy metals or poisonous chemicals in the functional food product.
- Applied results:
+ Successful creation of a functional food namedGYCRINfrom 04 medicinal plants assisted for prevention and treatment of cancer.

Some images of the projects:

thhanh1

Novelty and actuality and scientific meaningfulness of the results

+ Isolation and structural identification of 16 new compounds from 06 medicinal plants collected in Vietnam.
+ Creation of a functional food named GYCRIN from 04 medicinal plants assistedfor prevetion and treatment of cancer.

Products of the project

- Scientific papers in referred journals: published 03 ISI and 03 national papers
ISI papers
+ Nguyen ThiHuong, Le ThiVien, Tran Thi Hong Hanh, Nguyen Hai Dang, Nguyen Van Thanh,Nguyen Xuan Cuong, Nguyen Hoai Nam, Luu Hong Truong, NinhKhac Ban, Phan Van Kiem, Chau Van Minh. Triterpene saponins and megastigmane glucosides from Camellia bugiamapensis. Bioorganic & Medicinal Chemistry Letters 27 (2017) 557–561
+ Tran Thi Hong Hanh, Do Hoang Anh, Phan ThiThanhHuong, Nguyen Van Thanh, Nguyen Quang Trung, Tran Van Cuong, Nguyen Thi Mai, Nguyen The Cuong, Nguyen Xuan Cuong, Nguyen Hoai Nam, Chau Van Minh. Crinane, augustamine, and β-carboline alkaloids from Crinum latifolium. Phytochemistry Letters 24 (2018) 27–30.
+ Tran Thi Hong Hanh, Le ThiThuy Hang, Phan ThiThanhHuong, Nguyen Quang Trung, Tran Van Cuong, Nguyen Van Thanh, Nguyen Xuan Cuong, Nguyen Hoai Namand Chau Van Minh. Two new guaianesesquiterpene lactones from the aerial parts of Artemisia vulgaris. Journal of Asian Natural Products Research, 2017 (in press), https://doi.org/10.1080/10286020.2017.1356826.
- Patents: 01 Patent application
+ Chau Van Minh, Nguyen Hoai Nam, Phan Van Kiem, Nguyen Xuan Cuong, Tran Hong Quang, Tran Thi Hong Hanh, Do Thi Thao, Nguyen Quang Trung, Nguyen The Cuong. A cytotoxic compound (scutebarbatolide A) and a method to isolate this compound from Scutellariabarbata. Patent application No 1-2018-03423, the form of application was accepted by Decision No 68674/QĐ-SHTT dated October01st, 2018 of National Office of Intellectual Property of Vietnam.
- Technological products (describe in details: technical characteristics, place):
A functional food namedGYCRIN from 04 medicinal plants assistedfor prevention and treatment of cancer.

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