Study the scientific basis for the conversation and effective usage of Berberis wallichiana DC. and Mahonia bealei (Fortune) Pynaert of Berberidaceae Juss. in Viet Nam.

Project leader's name
Bui Van Thanh
Research hosting institution
Institute of Ecology and Biological Resources
Project duration
2015 - 2017
́Project’s budget
500.000.000 vnđ
Classify
Excellent
Goal and objectives of the project

Building the scientific basis for the conservation and sustainable use of plant resources in general and for two species of Berberis wallichiana DC. and Mahonia bealei (Fortune) Pynaert in particular.

Main results

* Theoretical results:
- Added more information on the biology, ecology,... of two species Berberis wallichiana DC and Mahonia bealei (Fortune) Pynaert in Vietnam;
- Developing a distribution prediction map for two species;
- Determining the chemical composition and biological activity of extracts from two research species.:
+ The chemical composition of the two species Mahonia bealei and Berberis wallichiana. A total of 16 compounds in which 3 new compounds were separated from Mahonia bealei; Six compounds were first reported from Berberis wallichiana;
+ Berberin compounds have toxic effects on prostate cancer DU145 and strong anti-inflammatory effect. 8-Oxypalmatine compound has strong effects on all three strains of lung A549, breast cancer MDA-MB-231 and prostate cancer DU145.
- Providing initial data on cutting multiplication and seed multiplication for two research species.
* Applied results:

Some images of the project:

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Novelty and actuality and scientific meaningfulness of the results

3 new compounds were separated from Mahonia bealei; Six compounds were first reported from Berberis wallichiana.

Products of the project

- Scientific pap

ers in referred journals (list): 01 articles in SCIE, 02 articles in local journals.
- Training: Training support 01 PhD student, 03 masters.
- Patents (list):
- Technological products (describe in details: technical characteristics, place):
- Other products (if applicable):
+ Reporting on research results on biological and ecological characteristics and status of exploitation and distribution Berberis wallichiana of 2 species of DC and Mahonia bealei (Fortune) Pynaert;
+ Reporting on separation results, determining the structure and biological activity of the clean compounds from the two research species;
+ Reporting on research results on cutting and seedling ability of 2 research species.
+ Set of specimens of the 2 species studied (stored in the Herbarium, Department of Botany, Institute of Ecology and Biological Resources).

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